Endocrine Abstracts

Introduction: Adipocytes have been shown to exhibit considerable heterogeneity. In humans, they vary in size from <20 to 300 µm in diameter, which equates to a several hundred-fold difference in cell volume within the same tissue. Population based studies indicate larger adipocytes are associated with metabolic diseases, but how cell size is related to metabolism is poorly understood. Recent studies measured glucose levels in individual cells in cultu...